A massive international genetic study has uncovered rare, high-effect variants in three specific genes-MAP1A, ANO8 and ANK2-that dramatically increase the likelihood of developing ADHD. These variants, though extremely uncommon, strongly affect genes expressed in dopaminergic and GABAergic neurons, influencing brain development from fetal life onward.
A massive international genetic study has uncovered rare, high-effect variants in three specific genes-MAP1A, ANO8 and ANK2-that dramatically increase the likelihood of developing ADHD. These variants, though extremely uncommon, strongly affect genes expressed in dopaminergic and GABAergic neurons, influencing brain development from fetal life onward.
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